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Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1
Coactivator associated arginine methyltransferase 1 (CARM1) is a member of the protein arginine methyltransferase (PRMT) family and methylates a range of proteins in eukaryotic cells. Overexpression of CARM1 is implicated in a number of cancers, and it is therefore seen as a potential therapeutic ta...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389282/ https://ncbi.nlm.nih.gov/pubmed/28330993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618401114 |
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