Intranasal immunization of pigs with porcine reproductive and respiratory syndrome virus-like particles plus 2′, 3′-cGAMP VacciGrade™ adjuvant exacerbates viremia after virus challenge

BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) causes reproductive failure in pregnant sows and acute respiratory disease in young pigs. It is a leading infectious agent of swine respiratory complex, which has significant negative economic impact on the swine industry. Comme...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Van Noort, Alexandria, Nelsen, April, Pillatzki, Angela E., Diel, Diego G., Li, Feng, Nelson, Eric, Wang, Xiuqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389191/
https://ncbi.nlm.nih.gov/pubmed/28403874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0746-0
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