Modulation of Macrophage Responses by CMX, a Fusion Protein Composed of Ag85c, MPT51, and HspX from Mycobacterium tuberculosis

Mycobacterium bovis Bacillus Calmette–Guérin (BCG) is a vaccine used to prevent tuberculosis (TB). Due to the poor protection conferred by BCG in adults, new, more effective formulations have been developed. A recombinant BCG vaccine expressing the CMX fusion protein Ag85c_MPT51_HspX (rBCG-CMX) indu...

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Publicado en:Front Microbiol
Autores principales: da Costa, Adeliane C., de Resende, Danilo P., Santos, Bruno de P. O., Zoccal, Karina F., Faccioli, Lúcia H., Kipnis, André, Junqueira-Kipnis, Ana P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389097/
https://ncbi.nlm.nih.gov/pubmed/28446902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00623
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