Immunogenicity of a Fusion Protein Containing Immunodominant Epitopes of Ag85C, MPT51, and HspX from Mycobacterium tuberculosis in Mice and Active TB Infection

Tuberculosis (TB) remains a major global health problem. The only vaccine against tuberculosis, attenuated Mycobacterium bovis Bacillus Calmette-Guerin (BCG), has demonstrated relatively low efficacy and does not provide satisfactory protection against the disease in adults. More effective vaccines...

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Detalhes bibliográficos
Main Authors: de Sousa, Eduardo Martins, da Costa, Adeliane Castro, Trentini, Monalisa Martins, de Araújo Filho, João Alves, Kipnis, André, Junqueira-Kipnis, Ana Paula
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485045/
https://ncbi.nlm.nih.gov/pubmed/23133523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047781
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