Low anti-staphylococcal IgG responses in granulomatosis with polyangiitis patients despite long-term Staphylococcus aureus exposure

Chronic nasal carriage of the bacterium Staphylococcus aureus in patients with the autoimmune disease granulomatosis with polyangiitis (GPA) is a risk factor for disease relapse. To date, it was neither known whether GPA patients show similar humoral immune responses to S. aureus as healthy carriers...

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Pubblicato in:Sci Rep
Autori principali: Glasner, Corinna, van Timmeren, Mirjan M., Stobernack, Tim, Omansen, Till F., Raangs, Erwin C., Rossen, John W., de Goffau, Marcus C., Arends, Jan P., Kampinga, Greetje A., Koedijk, Denny G. A. M., Neef, Jolanda, Buist, Girbe, Tavakol, Mehri, van Wamel, Willem J. B., Rutgers, Abraham, Stegeman, Coen A., Kallenberg, Cees G. M., Heeringa, Peter, van Dijl, Jan Maarten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389034/
https://ncbi.nlm.nih.gov/pubmed/25641235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08188
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