Low anti-staphylococcal IgG responses in granulomatosis with polyangiitis patients despite long-term Staphylococcus aureus exposure

Chronic nasal carriage of the bacterium Staphylococcus aureus in patients with the autoimmune disease granulomatosis with polyangiitis (GPA) is a risk factor for disease relapse. To date, it was neither known whether GPA patients show similar humoral immune responses to S. aureus as healthy carriers...

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Publicado no:Sci Rep
Main Authors: Glasner, Corinna, van Timmeren, Mirjan M., Stobernack, Tim, Omansen, Till F., Raangs, Erwin C., Rossen, John W., de Goffau, Marcus C., Arends, Jan P., Kampinga, Greetje A., Koedijk, Denny G. A. M., Neef, Jolanda, Buist, Girbe, Tavakol, Mehri, van Wamel, Willem J. B., Rutgers, Abraham, Stegeman, Coen A., Kallenberg, Cees G. M., Heeringa, Peter, van Dijl, Jan Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389034/
https://ncbi.nlm.nih.gov/pubmed/25641235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08188
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