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Antifungal Activities of R-135853, a Sordarin Derivative, in Experimental Candidiasis in Mice

The activities of R-135853, a novel sordarin derivative that possesses a 1,4-oxazepane ring moiety, were evaluated in vitro and in vivo. R-135853 exhibited potent in vitro activities against Candida albicans (fluconazole-susceptible strains), Candida glabrata, Candida tropicalis, and Cryptococcus ne...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Kamai, Yasuki, Kakuta, Masayo, Shibayama, Takahiro, Fukuoka, Takashi, Kuwahara, Shogo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2005
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616275/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.52-56.2005
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