Antifungal Activities of R-135853, a Sordarin Derivative, in Experimental Candidiasis in Mice

The activities of R-135853, a novel sordarin derivative that possesses a 1,4-oxazepane ring moiety, were evaluated in vitro and in vivo. R-135853 exhibited potent in vitro activities against Candida albicans (fluconazole-susceptible strains), Candida glabrata, Candida tropicalis, and Cryptococcus ne...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Kamai, Yasuki, Kakuta, Masayo, Shibayama, Takahiro, Fukuoka, Takashi, Kuwahara, Shogo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2005
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616275/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.52-56.2005
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