Molecular Cloning, Sequence Analysis, and Heterologous Expression of the Phosphinothricin Tripeptide Biosynthetic Gene Cluster from Streptomyces viridochromogenes DSM 40736

A fosmid library from genomic DNA of Streptomyces viridochromogenes DSM 40736 was constructed and screened for the presence of genes known to be involved in the biosynthesis of phosphinothricin tripeptide (PTT). Eight positives were identified, one of which was able to confer PTT biosynthetic capabi...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Blodgett, Joshua A. V., Zhang, Jun Kai, Metcalf, William W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2005
Schlagworte:
Chemistry; Biosynthesis
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538901/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616300/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.230-240.2005
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