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Scalable Downstream Strategies for Purification of Recombinant Adeno-Associated Virus Vectors in Light of the Properties

Recombinant adeno-associated virus (rAAV) vector is one of the promising delivery tools for gene therapy. Currently, hundreds of clinical trials are performed but the major barrier for clinical application is the absence of any ideal large scale production technique to obtain sufficient and highly p...

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Détails bibliographiques
Publié dans:Curr Pharm Biotechnol
Auteurs principaux: Qu, Weihong, Wang, Mingxi, Wu, Yaqing, Xu, Ruian
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388796/
https://ncbi.nlm.nih.gov/pubmed/25941887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389201016666150505122228
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