Exploring the Role of CYP3A4 Mediated Drug Metabolism in the Pharmacological Modulation of Nitric Oxide Production

Nitric-oxide synthase, the enzyme responsible for mammalian nitric oxide generation, and cytochrome P450, the major enzymes involved in drug metabolism, share striking similarities. Therefore, it makes sense that cytochrome P450 drug mediated biotransformations might play an important role in the ph...

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Podrobná bibliografie
Vydáno v:Front Pharmacol
Hlavní autoři: Pérez-del Palacio, José, Díaz, Caridad, Vergara, Noemí, Algieri, Francesca, Rodríguez-Nogales, Alba, de Pedro, Nuria, Rodríguez-Cabezas, M. Elena, Genilloud, Olga, Gálvez, Julio, Vicente, Francisca
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388737/
https://ncbi.nlm.nih.gov/pubmed/28446877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00202
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