Exploring the Role of CYP3A4 Mediated Drug Metabolism in the Pharmacological Modulation of Nitric Oxide Production

Nitric-oxide synthase, the enzyme responsible for mammalian nitric oxide generation, and cytochrome P450, the major enzymes involved in drug metabolism, share striking similarities. Therefore, it makes sense that cytochrome P450 drug mediated biotransformations might play an important role in the ph...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Pérez-del Palacio, José, Díaz, Caridad, Vergara, Noemí, Algieri, Francesca, Rodríguez-Nogales, Alba, de Pedro, Nuria, Rodríguez-Cabezas, M. Elena, Genilloud, Olga, Gálvez, Julio, Vicente, Francisca
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388737/
https://ncbi.nlm.nih.gov/pubmed/28446877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00202
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