De Novo Generation of Cationic Antimicrobial Peptides: Influence of Length and Tryptophan Substitution on Antimicrobial Activity

Comparison of human immunodeficiency virus lentiviral lytic peptide 1 with other host-derived peptides indicates that antimicrobial properties of membrane-active peptides are markedly influenced by their cationic, hydrophobic, and amphipathic properties. Many common themes, such as Arg composition o...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Deslouches, Berthony, Phadke, Shruti M., Lazarevic, Vanja, Cascio, Michael, Islam, Kazi, Montelaro, Ronald C., Mietzner, Timothy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2005
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538858/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.316-322.2005
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