Rational Design of Engineered Cationic Antimicrobial Peptides Consisting Exclusively of Arginine and Tryptophan, and Their Activity against Multidrug-Resistant Pathogens

The emergence of multidrug-resistant (MDR) pathogens underscores the need for new antimicrobial agents to overcome the resistance mechanisms of these organisms. Cationic antimicrobial peptides (CAPs) provide a potential source of new antimicrobial therapeutics. We previously characterized a lytic ba...

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Detalhes bibliográficos
Main Authors: Deslouches, Berthony, Steckbeck, Jonathan D., Craigo, Jodi K., Doi, Yohei, Mietzner, Timothy A., Montelaro, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716171/
https://ncbi.nlm.nih.gov/pubmed/23507278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02218-12
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