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In Vivo Resistance of a Laboratory-Selected Aspergillus fumigatus Isolate to Amphotericin B

The fungal burdens (number of CFU per pair of lungs) in mice infected with Aspergillus fumigatus AB16.4 (for which the amphotericin B [AMB] MIC was elevated) and W73355 (drug-susceptible parent) were reduced by 21 and 81%, respectively, after 5 days of AMB treatment (2 mg/kg/day), indicating that AB...

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Main Authors: Manavathu, Elias K., Cutright, Jessica L., Chandrasekar, Pranatharthi H.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC538856/
https://ncbi.nlm.nih.gov/pubmed/15616327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.428-430.2005
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