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Blockade of RAGE ameliorates elastase-induced emphysema development and progression via RAGE-DAMP signaling

The receptor for advanced glycan end products (RAGE) has been identified as a susceptibility gene for chronic obstructive pulmonary disease (COPD) in genome-wide association studies (GWASs). However, less is known about how RAGE is involved in the pathogenesis of COPD. To determine the molecular mec...

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Podrobná bibliografie
Vydáno v:FASEB J
Hlavní autoři: Lee, Hanbyeol, Park, Jeong-Ran, Kim, Woo Jin, Sundar, Isaac K., Rahman, Irfan, Park, Sung-Min, Yang, Se-Ran
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388549/
https://ncbi.nlm.nih.gov/pubmed/28148566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601155R
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