Role of MGMT Methylation Status at Time of Diagnosis and Recurrence for Patients with Glioblastoma: Clinical Implications

BACKGROUND. MGMT methylation status represents a powerful prognostic factor in newly diagnosed glioblastoma (GBM). Recently, its role in recurrent tumors has also been suggested; however, few data investigating the stability of this biomarker during the clinical course of the disease are available....

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Brandes, Alba A., Franceschi, Enrico, Paccapelo, Alexandro, Tallini, Giovanni, De Biase, Dario, Ghimenton, Claudio, Danieli, Daniela, Zunarelli, Elena, Lanza, Giovanni, Silini, Enrico Maria, Sturiale, Carmelo, Volpin, Lorenzo, Servadei, Franco, Talacchi, Andrea, Fioravanti, Antonio, Pia Foschini, Maria, Bartolini, Stefania, Pession, Annalisa, Ermani, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2017
Assuntos:
Neuro‐Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388380/
https://ncbi.nlm.nih.gov/pubmed/28275120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0254
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