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Gemcitabine Conjugated Chitosan and Double Antibodies (Abc-GC-Gemcitabine Nanoparticles) Enhanced Cytoplasmic Uptake of Gemcitabine and Inhibit Proliferation and Metastasis In Human SW1990 Pancreatic Cancer Cells

BACKGROUND: Pancreatic cancer is considered a chemoresistant neoplasm with extremely dismal prognosis and gemcitabine treatment is associated with many side effects and poor overall survival. The study aimed at developing a new nanobioconjugate, which specifically delivered gemcitabine and anti-EGFR...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Xiao, Jun, Yu, Haibo
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388304/
https://ncbi.nlm.nih.gov/pubmed/28366930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.901292
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