Synergistic Interaction Between Phage Therapy and Antibiotics Clears Pseudomonas Aeruginosa Infection in Endocarditis and Reduces Virulence

BACKGROUND. Increasing antibiotic resistance warrants therapeutic alternatives. Here we investigated the efficacy of bacteriophage-therapy (phage) alone or combined with antibiotics against experimental endocarditis (EE) due to Pseudomonas aeruginosa, an archetype of difficult-to-treat infection. ME...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Oechslin, Frank, Piccardi, Philippe, Mancini, Stefano, Gabard, Jérôme, Moreillon, Philippe, Entenza, José M., Resch, Gregory, Que, Yok-Ai
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388299/
https://ncbi.nlm.nih.gov/pubmed/28007922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw632
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