Synergistic Interaction Between Phage Therapy and Antibiotics Clears Pseudomonas Aeruginosa Infection in Endocarditis and Reduces Virulence

BACKGROUND. Increasing antibiotic resistance warrants therapeutic alternatives. Here we investigated the efficacy of bacteriophage-therapy (phage) alone or combined with antibiotics against experimental endocarditis (EE) due to Pseudomonas aeruginosa, an archetype of difficult-to-treat infection. ME...

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Bibliografske podrobnosti
izdano v:J Infect Dis
Main Authors: Oechslin, Frank, Piccardi, Philippe, Mancini, Stefano, Gabard, Jérôme, Moreillon, Philippe, Entenza, José M., Resch, Gregory, Que, Yok-Ai
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Major Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388299/
https://ncbi.nlm.nih.gov/pubmed/28007922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw632
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