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BTB Protein Keap1 Targets Antioxidant Transcription Factor Nrf2 for Ubiquitination by the Cullin 3-Roc1 Ligase

The concentrations and functions of many eukaryotic proteins are regulated by the ubiquitin pathway, which consists of ubiquitin activation (E1), conjugation (E2), and ligation (E3). Cullins are a family of evolutionarily conserved proteins that assemble by far the largest family of E3 ligase comple...

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Detalhes bibliográficos
Main Authors: Furukawa, Manabu, Xiong, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538799/
https://ncbi.nlm.nih.gov/pubmed/15601839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.162-171.2005
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