Feasibility of melatonin for prevention of delirium in critically ill patients: a protocol for a multicentre, randomised, placebo-controlled study

INTRODUCTION: Delirium is highly prevalent in the intensive care unit (ICU) and is associated with adverse clinical outcomes. At this time, there is no drug that effectively prevents delirium in critically ill patients. Alterations in melatonin secretion and metabolism may contribute to the developm...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Burry, Lisa, Scales, Damon, Williamson, David, Foster, Jennifer, Mehta, Sangeeta, Guenette, Melanie, Fan, Eddy, Detsky, Michael, Azad, Azar, Bernard, Francis, Rose, Louise
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Intensive Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387939/
https://ncbi.nlm.nih.gov/pubmed/28363933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2016-015420
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