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Feasibility of melatonin for prevention of delirium in critically ill patients: a protocol for a multicentre, randomised, placebo-controlled study

INTRODUCTION: Delirium is highly prevalent in the intensive care unit (ICU) and is associated with adverse clinical outcomes. At this time, there is no drug that effectively prevents delirium in critically ill patients. Alterations in melatonin secretion and metabolism may contribute to the developm...

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Bibliographische Detailangaben
Veröffentlicht in:BMJ Open
Hauptverfasser: Burry, Lisa, Scales, Damon, Williamson, David, Foster, Jennifer, Mehta, Sangeeta, Guenette, Melanie, Fan, Eddy, Detsky, Michael, Azad, Azar, Bernard, Francis, Rose, Louise
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387939/
https://ncbi.nlm.nih.gov/pubmed/28363933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2016-015420
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