A Novel Intronic cis Element, ISE/ISS-3, Regulates Rat Fibroblast Growth Factor Receptor 2 Splicing through Activation of an Upstream Exon and Repression of a Downstream Exon Containing a Noncanonical Branch Point Sequence

Mutually exclusive splicing of fibroblast growth factor receptor 2 (FGFR2) exons IIIb and IIIc yields two receptor isoforms, FGFR2-IIIb and -IIIc, with distinctly different ligand binding properties. Several RNA cis elements in the intron (intron 8) separating these exons have been described that ar...

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Hlavní autoři: Hovhannisyan, Ruben H., Carstens, Russ P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC538792/
https://ncbi.nlm.nih.gov/pubmed/15601847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.250-263.2005
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