Mild Method for 2-Naphthylmethyl Ether Protecting Group Removal Using a Combination of 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and β-Pinene

[Image: see text] The use of a combination of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and β-pinene permits the removal of 2-naphthylmethyl (Nap) ether protecting groups on highly sensitive substrates. The reaction tolerates both acid and base sensitive protecting groups, and products are aff...

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Bibliographic Details
Published in:J Org Chem
Main Authors: Lloyd, Dina, Bylsma, Marissa, Bright, Danielle K., Chen, Xizhao, Bennett, Clay S.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2017
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387675/
https://ncbi.nlm.nih.gov/pubmed/28281755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b00065
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