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Growth Inhibition by the Tumor Suppressor p33ING1 in Immortalized and Primary Cells: Involvement of Two Silencing Domains and Effect of Ras

ING1 was identified as an inhibitor of growth and has been described as a tumor suppressor. Furthermore, the expression of ING1 is induced in senescent cells and antisense ING1 extends the proliferative life span of primary human fibroblasts. Cooperation of p33ING1 with p53 has been suggested to be...

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Autors principals: Goeman, Frauke, Thormeyer, Dorit, Abad, Maria, Serrano, Manuel, Schmidt, Oliver, Palmero, Ignacio, Baniahmad, Aria
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538761/
https://ncbi.nlm.nih.gov/pubmed/15601862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.422-431.2005
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