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tau4/tau c/AF-2 of the thyroid hormone receptor relieves silencing of the retinoic acid receptor silencer core independent of both tau4 activation function and full dissociation of corepressors.

Members of the thyroid hormone (TR)-retinoic acid receptor (RAR) subfamily of nuclear hormone receptors silence gene expression in the absence of hormone. Addition of cognate ligands leads to dissociation of corepressors, association of coactivators, and transcriptional activation. Here, we used the...

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Main Authors: Baniahmad, A, Thormeyer, D, Renkawitz, R
格式: Artigo
語言:Inglês
出版: 1997
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC232279/
https://ncbi.nlm.nih.gov/pubmed/9234683
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