Ku80 correlates with neoadjuvant chemotherapy resistance in human lung adenocarcinoma, but reduces cisplatin/pemetrexed-induced apoptosis in A549 cells

BACKGROUND: Ku80 is a DNA repair protein which involves in cell apoptosis and chemoresistance. However, it is unclear whether Ku80 correlates with the efficiency of neoadjuvant chemotherapy in human lung adenocarcinoma, and modulates cisplatin/pemetrexed-induced lung cancer cell apoptosis in vitro....

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Enregistré dans:
Détails bibliographiques
Publié dans:Respir Res
Auteurs principaux: Shang, Bin, Jia, Yang, Chen, Gang, Wang, Zhou
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387337/
https://ncbi.nlm.nih.gov/pubmed/28399858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0545-6
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