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Assembly of CNS Nodes of Ranvier in Myelinated Nerves Is Promoted by the Axon Cytoskeleton

Nodes of Ranvier in the axons of myelinated neurons are exemplars of the specialized cell surface domains typical of polarized cells. They are rich in voltage-gated sodium channels (Nav) and thus underpin rapid nerve impulse conduction in the vertebrate nervous system [1]. Although nodal proteins cl...

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Pubblicato in:Curr Biol
Autori principali: Brivio, Veronica, Faivre-Sarrailh, Catherine, Peles, Elior, Sherman, Diane L., Brophy, Peter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387178/
https://ncbi.nlm.nih.gov/pubmed/28318976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.01.025
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