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oxLDL antibody inhibits MCP‐1 release in monocytes/macrophages by regulating Ca(2+)/K(+) channel flow

oxLDL peptide vaccine and its antibody adoptive transferring have shown a significantly preventive or therapeutic effect in atherosclerotic animal model. The molecular mechanism behind this is obscure. Here, we report that oxLDL induces MCP‐1 release in monocytes/macrophages through their TLR‐4 (Tol...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Su, Jinyu, Zhou, Hui, Liu, Xianyan, Nilsson, Jan, Fredrikson, Gunilla Nordin, Zhao, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387129/
https://ncbi.nlm.nih.gov/pubmed/27995732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13033
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