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Thymic DCs derived IL-27 regulates the final maturation of CD4(+) SP thymocytes
IL-27, as a pleiotropic cytokine, promotes the differentiation of naïve T cells to Th1, while suppressing Th2 and Th17 differentiation in the periphery. However, the role of IL-27 in the thymocyte development remains unknown. Here we showed that IL-27 was highly expressed in thymic plasmacytoid dend...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5387111/ https://ncbi.nlm.nih.gov/pubmed/27469302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30448 |
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