Nonhepatic Cell Lines HeLa and 293 Support Efficient Replication of the Hepatitis C Virus Genotype 2a Subgenomic Replicon

The hepatitis C virus (HCV) genotype 2a subgenomic replicon can replicate in two human non-hepatocyte-derived cell lines, HeLa and 293, with in vitro-transcribed replicon RNA. Sequencing analysis revealed that mutations in HCV-derived regions were not essential for replication in these cells, as som...

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में प्रकाशित:	J Virol
मुख्य लेखकों:	Kato, Takanobu, Date, Tomoko, Miyamoto, Michiko, Zhao, Zijiang, Mizokami, Masashi, Wakita, Takaji
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Microbiology (ASM) 2005
विषय:	Replication
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538706/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15596851/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.1.592-596.2005
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