High PTEN gene expression is a negative prognostic marker in human primary breast cancers with preserved p53 function

PURPOSE: PTEN is an important tumor suppressor in breast cancer. Here, we examined the prognostic and predictive value of PTEN and PTEN pseudogene (PTENP1) gene expression in patients with locally advanced breast cancer given neoadjuvant chemotherapy. METHODS: The association between pretreatment PT...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Yndestad, Synnøve, Austreid, Eilin, Knappskog, Stian, Chrisanthar, Ranjan, Lilleng, Peer Kåre, Lønning, Per Eystein, Eikesdal, Hans Petter
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387035/
https://ncbi.nlm.nih.gov/pubmed/28213783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4160-5
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