A carregar...

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

De novo mutations in CHD8 are strongly associated with autism spectrum disorder (ASD), however the basic biology of CHD8 remains poor understood. Here we report that Chd8 knockdown during cortical development results in defective neural progenitor proliferation and differentiation that ultimately ma...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Durak, Omer, Gao, Fan, Kaeser-Woo, Yea Jin, Rueda, Richard, Martorell, Anthony J., Nott, Alexi, Liu, Carol Y., Watson, L. Ashley, Tsai, Li-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386887/
https://ncbi.nlm.nih.gov/pubmed/27694995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4400
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!