ASPM regulates Wnt signaling pathway activity in the developing brain

Autosomal recessive primary microcephaly (MCPH) is a neural developmental disorder in which patients display significantly reduced brain size. Mutations in Abnormal Spindle Microcephaly (ASPM) are the most common cause of MCPH. Here, we investigate the underlying functions of Aspm in brain developme...

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Bibliografske podrobnosti
Main Authors: Buchman, Joshua J., Durak, Omer, Tsai, Li-Huei
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2011
Teme:
Research Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185963/
https://ncbi.nlm.nih.gov/pubmed/21937711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.16830211
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