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The E3 ubiquitin ligase NEDD4 is translationally upregulated and facilitates pancreatic cancer

AIM: To determine the regulation and function of the neural precursor cell expressed developmentally down regulated protein 4 (NEDD4) in PDAC and to determine its dependency on phosphatase and tensin homolog (PTEN) and PI3K/AKT signaling. METHODS: We investigated the expression of NEDD4 and the tumo...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Weng, Min, Luo, Zhu-Lin, Wu, Xiao-Ling, Zeng, Wei-Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386762/
https://ncbi.nlm.nih.gov/pubmed/28423617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15446
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