Inhibition activity of a disulfide-stabilized diabody against basic fibroblast growth factor in lung cancer

The over-expression of basic fibroblast growth factor (bFGF) plays a crucial role in the development, invasion and metastasis of lung cancer. Therefore, neutralizing antibodies against bFGF may inhibit the growth of lung cancer. In this study, a Disulfide-stabilized diabody (ds-Diabody) against bFGF...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Cai, Yaxiong, Yao, Shuange, Zhong, Jiangchuan, Zhang, Jinxia, Jiang, Haowu, Deng, Yanrui, Deng, Ning
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386754/
https://ncbi.nlm.nih.gov/pubmed/28423625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15556
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