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Construction of a disulfide‐stabilized diabody against fibroblast growth factor‐2 and the inhibition activity in targeting breast cancer

Fibroblast growth factor‐2 (FGF‐2) is one of the most important angiogenic factors to promote tumor growth, progression and metastasis. Neutralizing antibodies against FGF‐2 may suppress the growth of tumor cells by blocking the FGF‐2 signaling pathway. In this study, a disulfide‐stabilized diabody...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Cai, Yaxiong, Zhang, Jinxia, Lao, Xuejun, Jiang, Haowu, Yu, Yunfei, Deng, Yanrui, Zhong, Jiangchuan, Liang, Yiye, Xiong, Likuan, Deng, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982589/
https://ncbi.nlm.nih.gov/pubmed/27251178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12981
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