Construction of a disulfide‐stabilized diabody against fibroblast growth factor‐2 and the inhibition activity in targeting breast cancer

Fibroblast growth factor‐2 (FGF‐2) is one of the most important angiogenic factors to promote tumor growth, progression and metastasis. Neutralizing antibodies against FGF‐2 may suppress the growth of tumor cells by blocking the FGF‐2 signaling pathway. In this study, a disulfide‐stabilized diabody...

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Publicat a:Cancer Sci
Autors principals: Cai, Yaxiong, Zhang, Jinxia, Lao, Xuejun, Jiang, Haowu, Yu, Yunfei, Deng, Yanrui, Zhong, Jiangchuan, Liang, Yiye, Xiong, Likuan, Deng, Ning
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982589/
https://ncbi.nlm.nih.gov/pubmed/27251178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12981
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