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HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E

Redifferentiation therapy with BRAF/MEK inhibitors to facilitate treatment with radioiodine represents a good choice for radioiodine-refractory differentiated thyroid carcinoma, but recent initial clinical outcomes were modest. MAPK rebound caused by BRAF/MEK inhibitors-induced activation of HER2/HE...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cheng, Lingxiao, Jin, Yuchen, Liu, Min, Ruan, Maomei, Chen, Libo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386727/
https://ncbi.nlm.nih.gov/pubmed/28423638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15773
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