Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells

Hyperactivation of the PI3K/AKT pathway is observed in most human cancer including lung carcinomas. Here we have investigated the role of miRNAs as downstream targets of activated PI3K/AKT signaling in Non Small Cell Lung Cancer (NSCLC). To this aim, miRNA profiling was performed in human lung epith...

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Pubblicato in:Oncotarget
Autori principali: Guerriero, Ilaria, D’Angelo, Daniela, Pallante, Pierlorenzo, Santos, Mafalda, Scrima, Marianna, Malanga, Donatella, De Marco, Carmela, Weisz, Alessandro, Laudanna, Carmelo, Ceccarelli, Michele, Falco, Geppino, Rizzuto, Antonia, Viglietto, Giuseppe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386676/
https://ncbi.nlm.nih.gov/pubmed/27880728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13432
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