Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex

Coliphage HK022 Nun blocks superinfection by coliphage λ by stalling RNA polymerase (RNAP) translocation specifically on λ DNA. To provide a structural framework to understand how Nun blocks RNAP translocation, we determined structures of Escherichia coli RNAP ternary elongation complexes (TECs) wit...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Kang, Jin Young, Olinares, Paul Dominic B, Chen, James, Campbell, Elizabeth A, Mustaev, Arkady, Chait, Brian T, Gottesman, Max E, Darst, Seth A
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2017
Sujets:
Biochemistry
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386594/
https://ncbi.nlm.nih.gov/pubmed/28318486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25478
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