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Over-expression of phage HK022 Nun protein is toxic for Escherichia coli

The Nun protein of coliphage HK022 excludes superinfecting λ phage. Nun recognizes and binds to the N utilization (nut) sites on phage λ nascent RNA and induces transcription termination. Over-expression of Nun from a high-copy plasmid is toxic for E.coli, despite the fact that nut sites are not enc...

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Autori principali: Uc-Mass, Augusto, Khodursky, Arkady, Brown, Lewis, Gottesman, Max E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597491/
https://ncbi.nlm.nih.gov/pubmed/18571198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.030
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