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Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4
Coordination of energy metabolism is essential for homeostasis of stem cells, whereas an imbalance in energy homeostasis causes disease and accelerated aging. Here we show that deletion or enzymatic inactivation of lysine-specific demethylase 1 (Lsd1) triggers senescence in trophoblast stem cells (T...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5386490/ https://ncbi.nlm.nih.gov/pubmed/28230862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.48 |
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