Mesenchymal stromal cells inhibit CD25 expression via the mTOR pathway to potentiate T-cell suppression

Mesenchymal stromal cells (MSCs) are known to suppress T-cell activation and proliferation. Several studies have reported that MSCs suppress CD25 expression in T cells. However, the molecular mechanism underlying MSC-mediated suppression of CD25 expression has not been fully examined. Here, we inves...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Yoo, Hyun Seung, Lee, Kyuheon, Na, Kwangmin, Zhang, Yong Xu, Lim, Hyun-Ja, Yi, TacGhee, Song, Sun U, Jeon, Myung-Shin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386489/
https://ncbi.nlm.nih.gov/pubmed/28230853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.45
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