Mesenchymal stromal cells inhibit CD25 expression via the mTOR pathway to potentiate T-cell suppression

Mesenchymal stromal cells (MSCs) are known to suppress T-cell activation and proliferation. Several studies have reported that MSCs suppress CD25 expression in T cells. However, the molecular mechanism underlying MSC-mediated suppression of CD25 expression has not been fully examined. Here, we inves...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yoo, Hyun Seung, Lee, Kyuheon, Na, Kwangmin, Zhang, Yong Xu, Lim, Hyun-Ja, Yi, TacGhee, Song, Sun U, Jeon, Myung-Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386489/
https://ncbi.nlm.nih.gov/pubmed/28230853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.45
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