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ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells

Mesenchymal stem cells (MSCs) can modulate lymphocyte proliferation and function. One of the immunomodulatory functions of MSCs involves CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs), which negatively regulate inflammatory responses. MSC-mediated Treg induction is supposed to be regulated by mech...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Hyun-Joo, Kim, Si-Na, Jeon, Myung-Shin, Yi, TacGhee, Song, Sun U.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349520/
https://ncbi.nlm.nih.gov/pubmed/28290526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44486
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