Duodenal GLP-1 signaling regulates hepatic glucose production through a PKC-δ-dependent neurocircuitry

Intestinal glucagon-like peptide-1 (GLP-1) is a hormone that stimulates insulin secretion and acts as a neuropeptide to control glucose homeostasis, but little is known whether intestinal GLP-1 has any effect in the control of hepatic glucose production (HGP). Here we found that intraduodenal infusi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yang, Mengliu, Wang, Jinzhi, Wu, Shaobo, Yuan, Lei, Zhao, Xiaodong, Liu, Chaohong, Xie, Jing, Jia, Yanjun, Lai, Yerui, Zhao, Allan Zijian, Boden, Guenther, Li, Ling, Yang, Gangyi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386475/
https://ncbi.nlm.nih.gov/pubmed/28182013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.28
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