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Tenovin-6 impairs autophagy by inhibiting autophagic flux
Tenovin-6 has attracted significant interest because it activates p53 and inhibits sirtuins. It has anti-neoplastic effects on multiple hematopoietic malignancies and solid tumors in both in vitro and in vivo studies. Tenovin-6 was recently shown to impair the autophagy pathway in chronic lymphocyti...
Guardat en:
| Publicat a: | Cell Death Dis |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5386474/ https://ncbi.nlm.nih.gov/pubmed/28182004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.25 |
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