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Mitochondrial respiratory dysfunction disturbs neuronal and cardiac lineage commitment of human iPSCs
Mitochondrial diseases are genetically heterogeneous and present a broad clinical spectrum among patients; in most cases, genetic determinants of mitochondrial diseases are heteroplasmic mitochondrial DNA (mtDNA) mutations. However, it is uncertain whether and how heteroplasmic mtDNA mutations affec...
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| Pubblicato in: | Cell Death Dis |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5386384/ https://ncbi.nlm.nih.gov/pubmed/28079893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.484 |
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