Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer’s disease

Intravenous immunoglobulin (IVIg) has been a candidate as a potential anti-amyloid immunotherapy for Alzheimer disease (AD) because it contains anti-amyloid β (Aβ) antibodies. Although several studies with IVIg in AD have been published, changing levels of Aβ efflux from the brain, or disaggregation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kasai, Takashi, Kondo, Masaki, Ishii, Ryotaro, Tanaka, Akihiro, Ataka, Suzuka, Shimada, Hiroyuki, Tomiyama, Takami, Mori, Hiroshi, Taylor, Mark, Allsop, David, Nakagawa, Masanori, Mizuno, Toshiki, Tokuda, Takahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386327/
https://ncbi.nlm.nih.gov/pubmed/28394917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174630
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